PURPOSE: The objective of this study was to report and
evaluate our experience in the surgical treatment of mandibular
central giant cell granuloma by resection without continuity
defect and peripheral ostectomy.
METHODS: A retrospective analysis was conducted of
patients with central giant cell granuloma of the mandible who
were treated between 1991 and 2000, in the Oral and
Maxillofacial Surgery Unit at Jordan University of Science and
Technology. A uniform surgical technique was used in all cases.
The compact bone composed of the lower border of the mandible
and/or posterior border of the ascending ramus, together with
the nutrient periosteum attached to it, was preserved. All soft
tissues in contact with or overlying the lesion and a margin of
cancellous bone related to the lesion were excised. All patients
were reviewed annually for a follow-up period of 1 to 9 years
(mean, 3.9 years).
RESULTS: Eighteen patients with central giant cell
granuloma were included, (9 males and 9 females). Their age
ranged from 10 to 46 years, with 89% younger than 40 years. Five
(28%) lesions were in the incisor-canine region, 2 (11%) were
confined to the premolar region, 4 (22%) were in the
premolar-molar region, and 7 (39%) were in the molar-ramus
region. All patients had aggressive central giant cell
granulomas with pain, tooth mobility, and rapidly enlarging
swelling. The initial diameter of lesions ranged from 2.7 to 10
cm. During the follow-up period, there was 1 case of recurrence,
2 (11%) patients had permanent lower lip paraesthesia, and no
patient had obvious facial deformity.
CONCLUSION: Our results suggest that resection without a
continuity defect and peripheral ostectomy is a satisfactory
method in the treatment of central giant cell granuloma of the
mandible, with no or a very low recurrence rate and favorable
postoperative function. Copyright 2002 American Association of
Oral and Maxillofacial Surgeons.
Department of Oral and Maxillofacial Surgery, Faculty of
Dentistry, Jordan University of Science and Technology, PO Box
3030, Irbid, Jordan. firstname.lastname@example.org