The causes of chronic renal failure (CRF) vary from one country
to another. In this study we reviewed our experience with the
different types of renal disorders leading to CRF in Jordanian
METHODS: We investigated CRF in 202 Jordanian children
(113 males and 89 females) who presented to the Jordan
University Hospital, Amman, in the period from July 1988 to
April 2001. The mean age at onset of CRF was 7.5 +/- 3.9 years.
Patients were followed for 0.6-12.6 years (mean 6.3 years).
RESULTS: The causes of CRF included urological
abnormalities and malformations (42.1%), hereditary renal
disorders (29.7%), glomerulonephritis (GN)(14.4%), renal hypo-
or dysplasia (5%), hemolytic uremic syndrome (HUS) (4.5%), and
idiopathic (4.5%). Forty-nine patients required renal
replacement therapy, most of them with peritoneal dialysis. Nine
patients have undergone renal transplantation. We estimated the
prevalence of CRF in children in Jordan to be 51 per million
population, and the incidence as 10.7 new cases per
million-child population per year.
CONCLUSION: The high rate of hereditary disorders in our
series is attributed to the high prevalence of parental
consanguinity in our community. There was a striking number of
patients with non-neurogenic neurogenic bladder in our study.
The relative incidence of GN leading to CRF in Jordan is lower
than in Europe and North America. The relative incidence of the
other causes of CRF in our series is similar to many other
countries. The incidence and prevalence of CRF in children in
Jordan is high compared to other countries.
Department of Pediatrics, Jordan University Hospital, Amman.